Plasma Digosin Concentration in Dogs with Mitral Regurgitation.

Evaluation of diastolic blood flow dynamic of the left ventricle in dogs with mitral valve regurgitation using vector flow mapping

Mitral valve regurgitation (MVR) is a common valvular disease in dogs. Hydrokinetic evaluation of the blood flow within the ventricles has become possible by vector flow mapping (VFM), which shows the blood flow within the ventricles in vector and vortex flows. Blood flow within the left ventricle of MVR dogs was compared at different stages of MVR and to that of normal dogs. 14 normal dogs and...

Association of plasma N-terminal pro-B-type natriuretic peptide concentration with mitral regurgitation severity and outcome in dogs with asymptomatic degenerative mitral valve disease.

BACKGROUND The clinical outcome of dogs affected by degenerative mitral valve disease (MVD) without overt clinical signs is still poorly defined, and criteria for identification of animals that are at a higher risk of early decompensation have not yet been determined. HYPOTHESIS N-terminal pro-B-type natriuretic peptide plasma concentration (NT-proBNP) is correlated with mitral regurgitation ...

General anesthesia with remifentanil for cesarean section in a parturient with severe mitral and tricuspid regurgitation

Valvular heart lesions have deleterious effects on hemodynamics in parturients during pregnancy. Cesarean section with an opioid-based general anesthesia is used to alleviate the adverse effects. We described a case of a 28-year-old primigravida at 37 weeks’ gestation with a diagnosis of severe mitral regurgitation, tricuspid regurgitation, and pulmonary hypertension in active labor. Cesarean s...

Diagnostic Imaging of Cardiopulmonary Structures in Normal Dogs and Dogs with Mitral Regurgitation

Effects of pimobendan for mitral valve regurgitation in dogs.

Pimobendan has a dual mechanism of action: it increases myocardial contractility by increasing calcium sensitization to troponin C and it promotes vasodilation by inhibiting PDEIII. This study examined the effects of pimobendan on cardiac function, hemodynamics, and neurohormonal factors in dogs with mild mitral regurgitation (MR). The dogs were given 0.25 mg/kg of pimobendan orally every 12 hr...